A Discovery Platform for Next-Gen Drug Innovations

Shuimu is a rapidly evolving global cryo-EM & AI platform dedicated to early drug discovery. Equipped with 8 state-of-the-art 300kV cryo-EM instruments, Shuimu drives innovation to accelerate the development of groundbreaking drugs.

Better Accessibility

With eight 300kV TEMs at full load, we are expanding capacity to make cryo-EM more accessible to our partners around the world.

Competent Team & Techs

We invest in the top cryo-EM experts and innovative technologies to deliver quality cryo-EM projects and realize better applicability of the technique to various protein targets.

One-Stop Capability

Our platform consists of powerful cryo-EM data collection centers and an in-house protein production laboratory, capable of providing one-stop solutions for sequence to structure projects.

Shuimu Cryo-EM Platform

Image Description
Image Description
Image Description


Started with a belief in cryo-EM

Image Description
Hongwei Wang, PhD
Chair of Shuimu Scientific Advisory BoardDean of Institute of Biomedicine, Tsinghua University. 20+ year experience in cryo-EM methodology and its application in structural biology.
Image Description
Qiangfeng Zhang, PhD
Director of Shuimu Research InstituteProfessor at School of Life Sciences, Tsinghua University. Developer of modelSMART, a deep learning algorithm for atomic structure modeling.
Image Description
Allen Guo
CEOSerial entrepreneur, and seasoned investor with over 20 years of experience in the technology industry.

Scientific Advisory Board

On the shoulders of great minds we jump

Image Description
Yifan Cheng, PhD
Cryo-EM ScientistMember of AAAS and NAS, Professor at UCSF, Investigator of HHMI, Developed a direct electron detection camera in cryo-EM and significantly improved SPA resolution to 3.4 Å.
Image Description
Xueming Li, PhD
Expert in Electron Microscope & Data ProcessingProfessor at School of Life Sciences, Tsinghua University. Expert in electron microscopes and data processing.
Image Description
Jianlin Lei, PhD
Expert in Cryo-EM PlatformDirector of Cryo-EM Platform at Tsinghua University. Developer of AutoEMation, an automated data collection software.
Image Description
Hai Qi, PhD
ImmunologistDean of School of Medicine, Tsinghua University. Promoted the renewal and revision of Tfh generation mechanism and development theory.
Image Description
Guangshuo Ou, PhD
Cell BiologistProfessor at School of Life Sciences, Tsinghua University. Committed to structural biology research based on nematode models.
Image Description
Li Yu, PhD
Cell BiologistProfessor at School of Life Sciences, Tsinghua University. Discoverer of a new organelle migrating body.


Shuimu is a place for innovators and pioneers of tomorrow.

Send us a message

Connect with Us. Make Great Things Happen Together.

To inquire about our services, simply fill out this form and we'll be in touch.

See Unseeable.
Drug Undruggable.

Founded in 2017, Shuimu BioSciences aims to bring the power of cryo-EM to innovative therapeutics developers.


1 Broadway 5th floor, Cambridge, MA 02142, United States+1 (650) 680 9298


Copyright © 2024 Shuimu Biosciences Ltd.