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unlocking the secrets of biomacromolecules

Cryo-EM
Single Particle Analysis

Leveraging our advanced cryo-EM facility and expert team, Shuimu BioSciences excels in Single Particle Analysis, delivering precise high-resolution structures for drug formulation and gene therapy. With over 2000 SPA projects completed and resolutions reaching down to 1.4Å, we lead the way in advancing structural biology and drug discovery.
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CryoEM at Shuimu CryoEM Center

application

Cryo-EM SPA Application

Workflow

Cryo-EM SPA Workflow

Workflow

Why Choose Cryo-EM SPA?

Why choose Cryo-EM SPA

Why choose us?

Shuimu Cryo-EM SPA Advantages

GraFuture™ GO from Shuimu Biosciences

Advanced Cryo-EM Facility

The highest specs microscopes & advanced computing platform for high-quality structure determination
GraFuture™ RGO from Shuimu Biosciences

Cutting Edge Scientist Team

A team of PhD scientists from the top institutions, expertised in structural biology, protein science and computation

Profound Experience

2000+ cryo-EM projects experience, from membrane proteins to antigen-antibody complexes

Resolution Pursuit

1200+ protein structures determined at resolution better than 3.5Å: the best at 1.4Å and the smallest being 51kDA

What cases have we done?

Structures Solved by Shuimu

Our platform has delivered high-quality cryo-EM and microED structures to over 400 clients since 2017.
Cryo-EM SPACryo-EM SPACryo-EM SPAMicroEDMicroEDMicroED
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key milestones

Important Events

ICON
Over 1200 protein structures resolved at exceptional resolutions better than 3.5Å, showcasing our commitment to precision and accuracy in structural determination.
ICON
Extensive Project Portfolio Successfully completed 2000+ Single Particle Projects, demonstrating our proficiency and versatility in addressing diverse structural challenges.
ICON
Accomplished the structural elucidation of proteins as small as 51kDa, showcasing our expertise in handling a wide range of molecular sizes.
ICON
Pushing Boundaries Attained the highest resolution of 1.4Å, reflecting our dedication to pushing the boundaries of Cryo-EM technology.

TOOLKIT

Shuimu Technology

We've developed unique tool kits to excel in Cryo-EM structure determination.
GraFuture™

GraFuture™

Overcoming cryo-EM sample preparation challenges with reduced graphene oxide grids.
GraFuture™

modelSMART

Developing a differentiable neural network-based method for 3D atomic model identification.

Send us a message

Connect with Us. Make Great Things Happen Together.

To inquire about our services, simply fill out this form and we'll be in touch.

See Unseeable.
Drug Undruggable.

Founded in 2017, Shuimu BioSciences aims to bring the power of cryo-EM to innovative therapeutics developers.

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Contacts

1 Broadway 5th floor, Cambridge, MA 02142, United States+1 (650) 680 9383

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