unlocking the secrets of biomacromolecules
Cryo-EM
Single Particle Analysis
Single Particle Analysis (SPA) is a crucial cryo-EM structure determination technique that aids in determining hard-to-crystallize proteins in near-native states. By freezing biomacromolecule samples in vitreous ice, SPA provides high-resolution 3D structures of macromolecules, allowing structural characterization of small molecules with target proteins in drug discovery, antibody and antigen interaction studies, and more.
application
Cryo-EM SPA Application
Workflow
Cryo-EM SPA Workflow
Why Choose Cryo-EM SPA?
Why choose us?
Shuimu Cryo-EM SPA Advantages
Advanced Cryo-EM Facility
The highest specs microscopes & advanced computing platform for high-quality structure determination
Cutting Edge Scientist Team
A team of PhD scientists from the top institutions, expertised in structural biology, protein science and computation
Profound Experience
200+ cryo-EM projects experience, from membrane proteins to antigen-antibody complexes
Resolution Pursuit
150+ protein structures determined at resolution better than 3.5Å: the best at 1.8Å and the smallest being 51kDAWhat cases have we done?
Structures Solved by Shuimu
Our platform has delivered high-quality cryo-EM and microED structures to over 400 clients since 2017.
key milestones
Important Events
TOOLKIT
Shuimu Technology
We've developed unique tool kits to excel in Cryo-EM structure determination.
GraFuture™
Overcoming cryo-EM sample preparation challenges with reduced graphene oxide grids.
modelSMART
Developing a differentiable neural network-based method for 3D atomic model identification.See Unseeable.
Drug Undruggable.
Founded in 2017, Shuimu BioSciences aims to bring the power of cryo-EM to innovative therapeutics developers.Contacts
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